In-vitro biocompatibility evaluation of cast Ni–Ti alloy produced by vacuum arc melting technique for biomedical and dental applications

Abstract The investigated cast Ni50–Ti50 shape memory alloy was prepared using a vacuum arc furnace. samples were subjected to in-vitro biocompatibility studies according ISO 10993-12:2004, and compared other Ni–Ti orthodontic wires commercially available at the dental market. hydroxyapatite-coated electrodeposition technique. effect of surface treatment on coating quality addressed. electrochemical impedance (EIS) potentiodynamic techniques. Coated also examined scanning electron microscope inspect morphology. Cytotoxicity tests MG63 H9C2 cell lines showed safety NiTi alloy, with direct relationship between incubation period tested viability. Well-adhered hydroxyapatite obtained surface-treated EDS analysis having calcium phosphorus ratio close that natural bone. Electrochemical indicated highest corrosion resistance for uncoated followed by anodized sample finally due their high porosity.